at the
Nathan S Kline Institute for Psychiatric Research
and
News
-Winter 2025/26: The Hamm lab has posted a new preprint, showing that mismatch responses in visual cortex develop late, emerging after puberty in adolescence (>p42). This work also shows that fronto-visual connectivity develops along the same protracted timeline. And while microglia have been shown to support adolescent period frontal cortical development, we show that they are dispensable for the development of visual mismatch and related circuitry.
Winter 2025/26: The Hamm lab has posted a new preprint, showing that neural responses to visual stimuli in primary visual cortex are modulated by global predictability. This effect depended on higher level brain region (area ACa), and better explained classic oddball paradigms better than “local” context effects (i.e., recent stimulus history).
ABOUT THE HAMM LAB:
The neuroscience laboratory of Jordan Hamm is located at the Nathan S. Kline Institute for Psychiatric Research in the Emotional Brain Institute. The lab is accessible via shuttle leaving daily from either NYU or upper Manhattan and is a ≈15 minute drive from the George Washington Bridge.
We study the function of neocortex at the cell- and circuit-level, how it develops in adolescence, and how it’s altered in schizophrenia. Projects focus visual context processing, often through the lens of the predictive coding framework. We also focus on the developmental role of microglia in shaping neocortical circuitry. We work mainly in awake mouse models, both wild-type and transgenic. Primary techniques are two-photon calcium imaging, multielectrode recordings, opto/chemicogenetics, and behavior. We also carry out EEG studies in human populations, aimed at translating our rodent findings for interpretation and clinical perspective.
Please contact me directly for more information at hammj01 (at) nyu (dot) edu
or jordan.hamm (at) nki (dot) rfmh (dot) org
(or use the contact section).
Hamm Lab 